GLP-1 Tip: Make Yourself Available: Revision history

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21 December 2025

  • curprev 21:5121:51, 21 December 2025 WilliamByron6 talk contribs 3,652 bytes +3,652 Created page with "<br> The data support the existence of differences in the binding modes of GLP-1 and exendin-4 on the full-length GLP-1 receptor. Exendin-4 and GLP-1 are 50% identical, and exendin-4 is a full agonist with similar affinity and potency for the GLP-1 receptor. Interestingly, the isolated extracellular domain binds exendin-4 with much higher affinity than the endogenous agonist GLP-1. In a single randomized, double-blind, placebo-controlled trial, authors studied the effect..."
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